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J&J's ketamine-derived nasal spray approved by the FDA for the treatment of depression

J&J’s ketamine-derived nasal spray approved by the FDA for the treatment of depression

The Food and Drug Administration (FDA) approved Johnson & Johnson’s ketamine nasal spray to help millions of American patients suffering from severe depression. Spravato, approved as a stand-alone treatment, is “the first and only monotherapy for adults living with major depressive disorder who have had an inadequate response to at least two oral antidepressants,” the pharmaceutical giant said Tuesday. About 21 million U.S. adults live with major depressive disorder, one of the most common psychiatric disorders, but one-third of them will not respond to oral antidepressants alone, hampering their quality of life, according to Johnson & Johnson . “Treatment-resistant depression can be very complicated, especially for patients who do not respond to or cannot tolerate oral antidepressants. For too long, healthcare providers have had few options to provide patients with much-needed symptom relief,” Bill Martin, head of global therapeutics neuroscience at Johnson & Johnson Innovative Medicine, said in a statement. According to Johnson & Johnson, about 21 million adults in the US live with major depressive disorder. Getty Images Patients can experience improvements in their symptoms as early as 24 hours without the need for daily oral antidepressants. The approval, granted after FDA priority review, comes after more than a decade of research and nearly six years of real-world trials. As of Tuesday, it has been administered to more than 140,000 patients worldwide. The drug “has proven to be a transformative treatment option for many TRD patients by reducing depressive symptoms in as little as 24 hours and reducing relapse time for patients who remain on treatment,” the company said. Patients can experience improvements in their symptoms as early as 24 hours without the need for daily oral antidepressants. AFP via Getty Images There has been a growing use of ketamine – described as a “detachment drug” – to combat depression. It also made headlines for its use by high-profile figures, including Elon Musk. In March 2024, the head of Tesla and SpaceX said in an interview that he uses ketamine to enhance his mental health. “There are times when I have some kind of… a negative chemical state in my brain, like depression, I guess,” Musk said, adding that he uses a “small amount once a week.” There has been a growing use of ketamine – described as a “detachment drug” – to combat depression. AP “Ketamine is useful for getting a person out of a negative mindset,” Musk continued, referring to his depression as a “chemical tide” and saying it wasn’t “negative news.” However, off-label use of the drug has “skyrocketed” in recent years, “despite limited data supporting the safety and efficacy of this practice,” according to a report from the Yale School of Medicine. #JJs #ketaminederived #nasal #spray #approved #FDA #treatment #depressionImage Source : nypost.com

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The World's Busiest Trader Joe's is in NYC

The World’s Busiest Trader Joe’s is in NYC

This is pretty much everything but Bagel Spice. The busiest Trader Joe’s store in the world spans three levels and features three times the number of employees of the average location to handle the endless lines that sometimes stretch out onto the street. And if you thought this rafter-filled shop was somewhere in NYC, you’d be right. Despite only serving the city that never sleeps since 2006 — that’s the year the Southern California institution’s first branch opened to much fanfare at 142 E. 14th St., just off Union Square — the quirky alternative, tiki-themed traditional grocery shopping has been a big hit with New Yorkers. Trader Joe’s first opened in Manhattan in 2006. The Southern California-based chain has been a New York hit ever since. Bloomberg via Getty Images And while you may be convinced that your neighborhood branch is much more crowded on a Sunday afternoon, nowhere in the Big Apple beats the scene at 72nd and Broadway on the Upper West Side, according to reports. The often oversubscribed store at 2073 Broadway features four escalators (including trolleys, to make it easier to move between floors), two elevators and three times the registers of your average TJ’s location. Being a crew member in the favorite neighborhood means being an expert at crowd management and navigation to keep things from descending into chaos. Think Zabar, only on the road, but with more space and lines that are harder to cut. And because you’ll be spending most of your visit underground, don’t count on cell phone reception for open price comparisons, or last-minute inbound inquiries from home—customers report finding themselves in a without obstacles on a regular basis. In a ranking of every Manhattan Joe’s location compiled by Washington Square News, the Cacio E Pepe Puff building next door to Papaya Gray’s ranked near the bottom. A “Trader Joe” shopper takes her from the 72nd and Broadway store in Manhattan – said to be the busiest in the world. Getty Images Reviewers called it “weird”, saying it “spreads out like a maze” and that the flow “just feels wrong”. “The exit made us understand the value of urban planning. After shopping here, you’ll want to relax in nearby Central Park,” wrote critics Joey Hung and Sabrina Choudhary in 2021. Trader Joe’s was launched in the late 1960s in Pasadena, California, a short drive from downtown Los Angeles. The company was bought by Aldi founder Theo Albrecht in 1979 and is still owned by his descendants. There are currently more than 600 stores from coast to coast. The average Trader Joe’s ranges between 10,000 and 15,000 square feet. The 72nd and Broadway branch is thoroughly average in at least one way, with just 12,500 square feet of space. The smallest location is on Boylston Street in Boston—a claustrophobic 5,200 square feet. Trader Joe’s is known for fitting into unusual locations—from a decommissioned movie theater in Houston to a former bank branch in Brooklyn’s tony Cobble Hill neighborhood. #Worlds #Busiest #Trader #Joes #NYCImage Source : nypost.com

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How living near an airport can negatively affect your health

How living near an airport can negatively affect your health

Living near an airport can land you in the hospital. A new UK study highlights the significant health risks of constant exposure to airplane noise, which is bad news for the 40 million Americans who live near major airports. Researchers from University College London (UCL) analyzed the health records of 3,600 airport neighbors and 21,300 people who do not live near a flight path to examine the effects of significant and moderate aircraft turbulence compared to no noise. Past research has linked constant aircraft noise to sleep disturbances, increased stress, cognitive impairment in children, weight gain and a higher risk of high blood pressure and heart disease. Getty Images Residents exposed to the worst rockets, especially at night, had stiffer and thicker heart muscles that doubled or quadrupled the risk of a heart attack, life-threatening heart rhythm or stroke, the researchers said. “Our study is observational, so we can’t say for sure that high levels of aircraft noise caused these changes in heart structure and function,” said senior study author and cardiologist Dr. Gaby Captured. “However, our findings add to a growing body of evidence that aircraft noise can negatively affect heart health and our health in general,” added Captur. The loudest noise was defined as exceeding an average of 50 decibels during the day and 45 decibels between 11pm and 7am Fifty decibels is generally considered to be the equivalent of a fridge humming. The World Health Organization recommends limiting aircraft noise during the day to 45 decibels and nighttime noise to 40 decibels to avoid adverse health effects. Compared to the noise of roads or railways, planes tend to be louder and more unpredictable, so it is difficult to get used to them, the UCL researchers said. The new study found that those exposed to the worst aircraft noise, especially at night, had stiffer and thicker heart muscles that doubled or quadrupled the risk of a heart attack, a life-threatening heart rhythm or stroke. Getty Images Past research has linked constant aircraft noise to sleep disturbances, increased stress, cognitive impairment in children, weight gain and a higher risk of high blood pressure and heart disease. The UCL researchers attributed many of the changes in heart structure and function to obesity and high blood pressure (especially for those exposed to daytime noise). Among the study participants, 8% lived in an area with high noise during the day and 3% with high noise at night. Leaving the airport helped improve health. Get the latest medical breakthroughs, diet and nutrition tips, and more. Sign up for our weekly Post Care newsletter! Thanks for signing up! Participants who stayed in a high-noise area had 10% to 20% worse heart structure and function than those who moved, according to findings published Wednesday in the Journal of the American College of Cardiology. “For most of us, a plane is seen as a ticket to some well-deserved rest and relaxation,” said James Leiper, associate medical director at the British Heart Foundation. “But this innovative study reveals the potential unseen impact for those living near some of our biggest travel hubs.” UCL researchers are calling for further research into the lasting health effects of aircraft noise and government and industry solutions to reduce exposure to it. What to do if you live near an airport Dr. Michael Goyfman, chief of cardiology at Long Island Jewish Forest Hills Hospital, recommends healthy habits to reduce the risk of heart attack and stroke. Dr. Michael Goyfman, chief of cardiology at Long Island Jewish Forest Hills Hospital, shared some tips for staying healthy amid the noise above. Adopt good sleep habits, such as turning off electronic devices hours before bed and developing a consistent sleep schedule. If you’re worried about outside noise, try to exercise outside when there are fewer flights or go to a park further away from the airport. To reduce the risk of cardiovascular events such as heart attack or stroke, follow a healthy diet such as the Mediterranean diet, exercise 150 minutes a week, reduce stress through yoga or meditation, lower high blood pressure and stop smoking. #living #airport #negatively #affect #healthImage Source : nypost.com

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NewYork-Presbyterian opens new spine center in Hudson Yards skyscraper

NewYork-Presbyterian opens new spine center in Hudson Yards skyscraper

A state-of-the-art spine center from one of New York City’s top hospitals opened today in the new luxury Hudson Yards skyscraper. Och Spine at NewYork-Presbyterian/The Spiral occupies the entire second floor of The Spiral, which opened last year. With an area of ​​50,000 square feet, the spine center has 33 exam rooms, six procedure rooms and a 2,000 square foot rehabilitation gym. It is staffed by experts from Columbia University Irving Medical Center and Weill Cornell Medicine, who will be seeing patients in the same location for the first time. The Spine Center is on the second floor of The Spiral at Hudson Yards. NewYork-Presbyterian Hospital It is staffed by experts from Columbia University Irving Medical Center and Weill Cornell Medicine, who will be seeing patients in the same location for the first time. NewYork-Presbyterian Hospital NewYork-Presbyterian Hospital-Columbia and Cornell ranked first in US News & World Report’s 2024 ranking of New York City’s best hospitals. It was tied in a four-way tie with Mount Sinai Hospital, University Hospital North Shore at Northwell Health in Manhasset and NYU Langone Hospitals. Och Spine also has locations on the Upper East Side and in Inwood and Washington Heights. The new outpatient facility has areas for physical therapy, surgical and non-surgical procedures and radiology, complete with MRI machines, CT scanners, X-ray machines and an EOS machine, which creates 2D and 3D X-rays with low-dose radiation. The new outpatient facility has areas for physical therapy, surgical and non-surgical procedures and radiology. NewYork-Presbyterian Hospital Patients can see multiple specialists in a single visit. Out-of-center practitioners include orthopedic surgeons and neurologists, neurologists, physical medicine and rehabilitation physicians, pain management specialists, radiologists, and physical therapists. “This beautiful state-of-the-art facility is matched with world-class experts who will work side by side to provide comprehensive and personalized spine care,” Dr. Steven J. Corwin, president and CEO of NewYork-Presbyterian, said. Dr. Lawrence Lenke, co-director of Och Spine at NewYork-Presbyterian and chief of spine surgery at NewYork-Presbyterian/Columbia Irving University Medical Center, said the center “will allow us to care for the full spectrum of patients with backbone – locally, regionally, nationally and internationally – and help them get back into their lives and communities.” Patients can see multiple specialists in a single visit. NewYork-Presbyterian Hospital The new center – funded in part by the Jane and Daniel Och Family Foundation, which contributed $50 million – will treat conditions including scoliosis, spinal deformities, spinal injuries, degenerative spinal diseases and pain neck and back. Get the latest medical breakthroughs, diet and nutrition tips, and more. Subscribe to our weekly Post Care newsletter! Thanks for signing up! NewYork-Presbyterian signed a 20-year lease with Tishman Speyer, which paid $438 million for The Spiral site in 2014 and financed the project for $3.7 billion in 2018. The spiral is also home to HSBC, SEB Group, Debevoise & Plimpton, a law firm, Alliance Bernstein, an investment company, and Pfizer. The top floor of the building is home to ZO, a club lounge with an open-air terrace, pool tables and a cafe. #NewYorkPresbyterian #opens #spine #center #Hudson #Yards #skyscraperImage Source : nypost.com

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Two 'beloved' Girl Scout cookies are being discontinued

Two ‘beloved’ Girl Scout cookies are being discontinued

This is how the cookie crumbles! Kicking off the 2025 Girl Scout cookie season, the brand announced that this would be the last year customers can indulge in two flavors that taste like the perfect campfire. “At the close of the 2025 cookie season, two beloved cookie flavors, Girl Scout S’mores® and Toast-Yay!®, will be retired,” a spokesperson for Girl Scouts of the USA announced in a release to print. S’mores were introduced in 2017 as “crunchy graham crackers with chocolate and marshmallow filling Los Angeles Times via Getty Images The news, released on January 7, came as a shock to many who have been eating sweet treats since their debut. S’mores were introduced in 2017 as “crispy graham crackers with chocolate and marshmallow filling,” while Toast-Yay!, which debuted in 2021, was billed as “full of French toast flavor” dipped in cream. Removing cookies is not easy for fans. “Scout S’mores in retirement?! Humanity, this is why we can’t have nice things,” tweeted X user @realAthenaAI. Toast-Yay!, which debuted in 2021, was billed as “full of French toast flavor” dipped in cream. Los Angeles Times via Getty Images “It’s the final curtain call for the legendary S’mores and Toast-Yay! taste. This is not a workout…. get them before they are gone forever. Bundle up, flex your swag and enjoy the nostalgia!” wrote another X account holder, @doodxrpl. “I might have to get me some s’mores… these are the good versions like the ones my stepmom used to sell when she was a Girl Scout,” said a Girl Scout dad, @Wreckingcrue86. While many customers were put off by the bakery’s bad news, there are still some delicious flavors to choose from. The young ladies in green will be selling cookie flavors including Thin Mints, Samoas®/Caramel deLites, Peanut Butter/Tagalonge Dumplings, Adventurers, Chocolate Caramel Chips, Peanut Butter Sandwich Do-si-dos, lemonade, lemon-ups, candy canes. and Trefoils, until mid-April. Although Girl Scouts didn’t introduce any new flavors in this batch of cookies, customers can expect more sweet choices to come. “We routinely re-evaluate our cookie mix to make room for new innovations. Interrupting Toast-Yay! and Girl Scout S’mores® can lead to something new and delicious,” hinted a spokesperson. #beloved #Girl #Scout #cookies #discontinuedImage Source : nypost.com

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Why I love Martha Stewart's food packages

Why I love Martha Stewart’s food packages

New York Post may be compensated and/or receive an affiliate commission if you purchase through our links. Featured pricing may vary. Martha Stewart can do no wrong—well, at least when it comes to food. For those who don’t know, you can get pretty close to Martha being a living chef with her meal kit company, Martha Stewart & Marley Spoon. I’ve reviewed Marley Spoon before; when I was testing more than 20 other meal kits from 2020 to the end of 2024 for our 2025 refresh of my larger-than-life roundup – and while I may not have cooked as much as Martha, it feels a lot close! I wanted to give Marley Spoon a special shout out as one of the best gourmet options on the market. The kit uses only the freshest ingredients to create seasonal recipes that are sure to please. Not all meals are fancy pants, as Martha also knows that comfort food is just as important as good food. For that reason, many of the 100-plus recipes on the weekly menu are comfort classics like burgers, casseroles, stews—you get the idea. How Marley Spoon Works Sophie Cannon The kit is traditional, with more than 100 weekly recipes, with fresh ingredients delivered on your schedule. You can choose the two-person or four-person plan, and then choose the number of meals you need per week, from two to six. The ingredients come in a brown paper bag and the proteins come in ice packs to maintain freshness. Each box also includes all the easy-to-follow recipe cards that can be recycled or kept for later use. Marley spoon price Marley Spoon’s pricing varies, but traditionally starts at $8.69 and can go up to $12.99 per serving. Shipping is a flat rate of $11.99, regardless of box size. Be sure to check if your location is eligible for shipping, as some areas are not yet served by Marley Spoon. There are frequent Marley Spoon coupons, so be sure to check the site for incoming offers for discounts and free shipping. Sophie Cannon The pros: Delicious and high quality food – but what else would we expect from Marta? Perfect for the home cook who likes a balance of easy meals and learning new skills Great for home cooked dinners with simple instructions Options for specific diets, including vegetarian and low-carb recipes, in addition to classic comfort foods Sustainable packaging and practices Disadvantages: Be sure to check your zip code for delivery, as some areas in the Midwest and other countries are not eligible as of publication time. You may need to have extra ingredients on hand, especially for baking recipes Marley Spoon serves almost everything, as there are more than 100 options on the weekly menu, plus premium options with fancier ingredients and proteins, as well as frugal options for more affordable and stripped-down meals. There are also options on the site for appetizers, entrees, breakfast, and even dessert, which I tried during Halloween – yes, they offer some fun seasonal menu items and yes, they are all adorable! When you sign up, you can enjoy the full menu or be presented with selected dietary options, including gluten-free, low-calorie, low-carb, vegetarian, vegan and plant-based, as well as family-friendly. There is also a menu for picky eaters that limits spicy foods and more unusual ingredients. We have tried: When I broke down the ingredients, I loved how the included recipe cards listed everything, making it easier to sort through my fridge and know what extras I’d need, like butter, oil, vinegar, and some homemade spices. Be sure to check your fridge and pantry before you start. I ended up needing an egg and vanilla for a baking recipe. The cards also list the necessary cooking tools, as well as allergens and food per serving. Because these recipes are from Martha Stewart, I wasn’t surprised that many of them were more complex, requiring a lot of oven use. Note: cooking time may vary depending on your device, so keep that in mind if you’re in a hurry. For example, the breakfast I cooked in my old oven needed a lower temperature than listed, while the cookies took much less time in my powerful toaster oven. Other time variations can result from additional slicing, dicing, and fancy steps such as roasting nuts or pre-roasting vegetables. However, I was rewarded for my time and effort. Every recipe turned out great and tasted even better. The cookies took longer. I know ‘baking is a science’, but I still jumped a bit by adding a little extra spice to the custard filling. I also spent more on my pasta to make sure the soup was perfect before plating. I think Marta would be proud of the extra effort. Final decision The Marley Spoon is a gourmet meal kit, perfect for those who love the cooking process but not the grocery shopping part. The meals are all delicious and great for families, as there are options for larger portions and kid-friendly meals. Compared to other meal kits I’ve tested, this one had more options for weekly recipes, as well as more advanced meals for those who want to spend time improving their cooking skills. How we tested it Ease of ordering: When looking at the menu, Marley Spoon is simple to set up and order for each week. I always consider how to customize the order, make changes and stop a membership during testing. Preparation, cooking and cleaning time: A major selling point of meal kits is that they save time. Marley Spoon takes anywhere from 30 to 60 minutes per meal, sometimes more than the recipe estimates. I still noticed how long it took me to eat a full meal from unpacking to cooking, eating and recycling afterwards. Taste and fullness: Meal kits are meant to take all the guesswork out of cooking, including seasonings. When I tested the Marley Spoon, I considered whether any of the dishes I ordered needed to be seasoned or

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Viral 'flu bomb' drug clears illness in less than 24 hours

Viral ‘flu bomb’ drug clears illness in less than 24 hours

Grandma knows best. Health influencer and licensed lymphatic massage therapist Lo Reyez has gone viral with her abuela’s “flu bomb,” a combination of common ingredients that she swears will deliver unprecedented results if you want to shorten the length of time you’re sick. Noting that cold and flu season is in full swing — or sneeze, as it were — Reyez promised not to “hold the door” and offered her grandmother’s medicine. Lymphatic massage therapist Lo Reyez has shared her grandmother’s recipe for a “flu bomb.” @lo.reyez/TikTok And there’s never been a better time as flu rates continue to rise in New York and across the US. The flu has killed about 1,500 people across the country this season. According to the CDC, an additional 3.1 million people have reported contracting the flu, resulting in at least 37,000 hospitalizations. Addressing her 68,000 followers, Reyez promised that this DIY recipe could help you fight infections. “You guys, I’m telling you. “I’ve never been sick for more than 24 hours,” she said. Its one-size-fits-all treatment boasts accessible ingredients that emphasize antimicrobial and anti-inflammatory properties. “You better listen to Abuela. These are all-natural ingredients you can find in the kitchen or at the grocery store, and let me tell you, it will kill the flu, because nature knows best, baby!” Reyez’s medicine boasts accessible ingredients. @lo.reyez/TikTok Recipe for Abuela’s Flu Bomb: 2 tablespoons of ginger 1 tablespoon of turmeric 1 tablespoon of minced garlic 1 pinch of black pepper (to activate the turmeric) 1 pinch of cayenne pepper cinnamon (to taste) cover with honey Reyez says the mixture can be taken straight, a teaspoon at a time, or diluted in warm water and drunk. The flu bomb can be taken as a preventative or curative measure and, if sealed and refrigerated, can last up to three months. Get the latest medical breakthroughs, diet and nutrition tips, and more. Subscribe to our weekly Post Care newsletter! Thanks for signing up! In terms of ingredient efficacy, ginger is a natural expectorant with antimicrobial and antioxidant properties, while the capsaicin in cayenne pepper has been found to relieve congestion and sneezing. Garlic is rich in prebiotic insulin fiber, which supports gut health and is believed to have antimicrobial and antiviral properties. It also contains allicin, a natural antibiotic used to fight disease for thousands of years. One study found that people who took a garlic supplement for 12 weeks during the cold season had fewer colds and saw their symptoms resolve more quickly than those who didn’t. Meanwhile, honey is rich in antioxidants such as flavonoids and polyphenols, which help balance the immune system and prevent disease.. Turmeric contains curcumin, an ingredient known to have anti-inflammatory and antimicrobial properties. “This flu season is crazy, everyone stay safe,” Reyez urged. Commenters were quick to share their own variations of the remedy. “My mom makes the same mixture, but adds onions and lets it ferment all year round. Cleaned me up overnight,” shared one user. “Swear to it,” said another. “Thank goodness I saw this when I started feeling sick and it worked. Thank you very much!” another appreciative devotee noted. Reyez’s tonic shared some ingredient overlap with other natural remedies, including “Amish amoxicillin” and Australian alternative health advocate Barbara O’Neill’s viral recipe (no pun intended) for seven-ingredient flu bombs. #Viral #flu #bomb #drug #clears #illness #hoursImage Source : nypost.com

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Researchers discover 'aging tipping point' in the brain - and the fine could have huge implications for patients

Researchers discover ‘aging tipping point’ in the brain – and the fine could have huge implications for patients

The brain plays a major role in the aging process, and scientists think they have identified the specific cells that control it. In a study of mice, researchers at the Allen Institute identified certain cells that showed “profound changes” with age, particularly in a specific “hot spot,” according to a news release. Mice were chosen because their brains have “a lot of similarities” to the human brain. “Our brain is made up of thousands of cell types, which perform different functions,” Hongkui Zeng, co-author of the study and director of the Allen Institute for Brain Science in Seattle, told Fox News Digital. “Our study shows that different types of cells are differently susceptible to the aging process.” The research, funded by the National Institutes of Health, was published in the journal Nature. The researchers used RNA sequencing and brain mapping tools to analyze more than 1.2 million brain cells from young (2-month-old) and older (18-month-old) mice. 18-month-old mice are roughly equivalent to a “late middle-aged human,” the researchers said. The researchers grouped the cells into 847 different types and also identified nearly 2,500 genes that changed with aging, according to Zeng. The brain plays a major role in the aging process, and scientists think they have identified the specific cells that control it. merydolla – stock.adobe.com Cells that were associated with aging showed an increase in inflammation and a decrease in “neuronal function.” “Changes in these genes indicate deterioration of neuronal structure and function in many types of neuronal and glial cells, as well as increased immune response and inflammation in immune and vascular (blood vessel) cell types of the brain,” Zeng said. The cells that experienced the biggest changes were those in the hypothalamus, the part of the brain associated with food intake, energy balance and metabolism, the researchers noted. The researchers grouped the cells into 847 different types and also identified nearly 2,500 genes that changed with aging, according to the researchers. Dragana Gordic – stock.adobe.com This suggests that this area is an “aging hotspot,” Zeng noted, and that there may be a link between diet, lifestyle factors, brain aging, and the risk of age-related cognitive disorders. “Findings from the study reinforce the idea that maintaining a healthy lifestyle, promoting a healthy metabolic state, and reducing inflammation in the body and brain can slow or delay the aging process and reduce the risks of age-related brain diseases.” ,” he said. The hope is that this discovery could lead to new age-related therapies to improve the function of these cells and help prevent neurodegenerative diseases, according to the researchers. Get the latest medical breakthroughs, diet and nutrition tips, and more. Sign up for our weekly Post Care newsletter! Thanks for signing up! “Aging is the most important risk factor for many brain diseases,” Zeng noted. “Our study provides a highly detailed genetic map of which brain cell types may be most affected by aging and suggests new gene and cell targets for the development of new treatments for aging-related brain diseases.” “Changes in these genes indicate deterioration of neuronal structure and function in many types of neuronal and glial cells, as well as increased immune response and inflammation in immune and vascular (blood vessel) cell types of the brain,” Zeng said. sutadimages – stock.adobe.com The study had some limitations, the authors acknowledged. “The main limitation of our study is that the findings are correlational,” Zeng said. “We do not yet know whether the gene expression changes observed in specific cell types are responsible for brain aging. Our study lays the groundwork by providing a detailed genetic map and cell targets.” Mice were chosen because their brains have “a lot of similarities” to the human brain. file174 – stock.adobe.com Zeng called for future studies to investigate the roles of cells in aging and to determine whether reversing the changes can delay the aging process. Dr. Earnest Lee Murray, a board-certified neurologist at Jackson-Madison County General Hospital in Jackson, Tennessee, commented that the new research adds to existing evidence supporting the role of diet in human brain health. The detailed “brain road map” will be very useful for future research on aging and potential therapies, according to Murray, who was not involved in the study. “More and more evidence shows that many chronic diseases can be prevented, and this often depends on diet and exercise,” said Dr. Earnest Lee Murray. Photographee.eu – stock.adobe.com It has been known for some time that inflammation plays a role in chronic age-related diseases such as Alzheimer’s, the neurologist noted. “More and more evidence shows that many chronic diseases are preventable, and it often comes down to diet and exercise,” he told Fox News Digital. “Changing your diet to eliminate processed foods and starting certain habits like intermittent fasting has been shown to reduce this cellular inflammation that seems to be leading to so many diseases.” #Researchers #discover #aging #tipping #point #brain #fine #huge #implications #patientsImage Source : nypost.com

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I'm a Financial Planner - This is a Simple Money Habit You Need to Quit in 2025

I’m a Financial Planner – This is a Simple Money Habit You Need to Quit in 2025

New year, new habits. Shannon McLay, CEO of financial planning service The Financial Gym, is sharing the one spending habit people need to break in 2025. Emphasizing ‘awareness’, the money guru says it’s time to delete simple payment apps from your smartphone that allow you to make mindless purchases with just the click of a button. “I always say that we work really hard for every dollar that we make, so we have to make it hard to spend those dollars because it’s hard to get them in the bank,” she told TheStreet. “But it’s so easy for us to spend the money we spend on our phones. We spend it with credit cards on apps and we don’t realize where it’s going.” McLay said knowing “where your money is going” and being mindful of your spending is the first step to regaining control of your finances. Thapana_Studio – stock.adobe.com McLay says financial experts “hear all the time” that their clients “have no idea” where their money is going, with many saying they “make it and then it’s gone.” She encourages people to be aware of their money, even though it often causes anxiety. “We see people who seem very financially healthy to us and they’re feeling anxious,” she said. “And when we feel anxious about an area, we avoid it. We don’t want to dig into the thing that’s creating the anxiety.” A previous study found that 73% of Americans are stressed about finances. Pixel-Shot – stock.adobe.com As a result, people “won’t look” at where their income is going. A study last year found that 73% of Americans are stressed about their finances. “So that’s one of the first steps we would say is being aware of where your money is going and whether it’s tracking your spending through an app or even just manually tracking it in the Notes app on the phone yours,” advised McLay. “That process of paying attention to where your money is going is a really good first step.” Gen Z has also ushered in another financially savvy trend — “loud budgeting,” or being transparent about finances. “They say there’s no shame and guilt in their financial situation,” financial expert Julie O’Brien, senior vice president and head of behavioral science at US Bank, previously told Money. “But it’s so easy for us to spend the money we spend on our phones. We spend it with credit cards on apps and we don’t realize where it’s going,” McLay said. Romantic Studio – stock.adobe.com “They’re just saying out loud that healthy management of their money is something they value more than consumerism and the curated, unrealistic ideals they see portrayed.” #Financial #Planner #Simple #Money #Habit #QuitImage Source : nypost.com

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Bryan Johnson's shocking health regimen he shares with his son

Bryan Johnson’s shocking health regimen he shares with his son

What a father figure! Bryan Johnson, the 47-year-old tech millionaire who has poured millions into his quest for immortality, has revealed the strict daily longevity routine he shares with his son, Talmage, 19. The pair – who have been praised for looking “like brothers” – shocked the world in 2023 when they announced they had carried out the “world’s first multi-generational plasma exchange”, along with Johnson’s father, now 71, in an effort to remain forever young. . Following the release of his new Netflix documentary, “Don’t Die: The Man Who Wants to Live Forever,” Johnson took to X on Thursday to explain how to “build a family culture of health and hard work.” The pair shocked the world in 2023 when they announced they had undergone “the world’s first multi-generational plasma exchange”, along with Johnson’s father, now 71. Bryan Johnson/YouTube Start with the basics: Johnson and Talmage wake up at 5 a.m., eat their “last meal of the day,” a combination of vegetables, nuts, seeds and berries, at noon and go to bed at 8:30 p.m. Johnson has poured millions into his quest for immortality. YouTube/, Diary of a CEO “By the time I go to bed at 8:30 p.m., primary digestion is done and my resting heart rate is about 47-49 beats per minute,” Johnson recently said on his website. “If I eat later in the day, my resting heart rate will be between 55-58 beats/min because my body is still digesting food and it will reduce the quality of my sleep by 30%. When he hits the grass, there’s little sway, as Johnson enjoys a lot of deep and REM sleep. He said he was able to achieve “perfect sleep” in part by performing an evening shutdown ritual and cutting out late-night activities. He also does not consume caffeine or alcohol. Johnson tests a device he claims can simulate the effects of doing 20,000 push-ups. Instagram / bryanjohnson_ It’s no wonder that father and son thrive on Johnson’s Blueprint stack, his comprehensive supplement program that’s available on Amazon. Johnson’s powerful protocol contains metformin for blood glucose regulation and proferrin for iron and red blood cell production. He follows a vegan diet except for collagen peptides. He usually consumes 2250 calories per day, 130 grams of protein, 206 carbohydrates and 101 grams of fat. Breakfast is a protein blend with cocoa, extra virgin olive oil and macadamia nut milk, while lunch at 9am is a super veggie bowl. Get the latest medical breakthroughs, diet and nutrition tips, and more. Sign up for our weekly Post Care newsletter! Thanks for signing up! The fitness duo does a daily 60-minute workout that combines strength, cardio, flexibility and balance. Reverse push-ups, pull-ups, squats, bicep curls and 10 minutes of high-intensity interval training (HIIT) are among the exercises on the docks. And finally, the pair engages in “focused work.” When asked about the documentary about his relationship with Talmage, Johnson said that, “Talmage sees me as his future self and I see Talmage as my former self.” “I think we’re both just talking to ourselves when we’re engaged in our conversations,” he added. Johnson and Talmage train for an hour a day. Bryan Johnson/X The Netflix interviewer joked, “I thought you were going to say you see Talmage as your future self.” “Yeah, in a lot of ways, that’s true,” Johnson laughed. #Bryan #Johnsons #shocking #health #regimen #shares #sonImage Source : nypost.com

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